Polymer Humectant: Super Hyaluronic Acid

Hyaluronic Acid Hydrogel Materials

This chapter discusses two protocols that are used throughout the remaining chapters. These protocols and experimental data comprise the early preliminary work of this dissertation. The first protocol is the synthesis of photocrosslinkable glycidyl methacrylate modified hyaluronic acid (GMHA). This derivative was synthesized by the reaction of glycidyl methacrylate with HA in a solvent mixture ...

Hyaluronic acid (hyaluronan)

Chitosan-Based Hyaluronic Acid Hybrid Polymer Fibers as a Scaffold Biomaterial for Cartilage Tissue Engineering

An ideal scaffold material is one that closely mimics the natural environment in the tissue-specific extracellular matrix (ECM). Therefore, we have applied hyaluronic acid (HA), which is a main component of the cartilage ECM, to chitosan as a fundamental material for cartilage regeneration. To mimic the structural environment of cartilage ECM, the fundamental structure of a scaffold should be a...

Coefficient of Friction Between Carboxymethylated Hyaluronic Acid-Based Polymer Films and the Ocular Surface.

Purpose Hyaluronic acid-based polymer films are emerging as drug-delivery vehicles for local and continuous drug administration to the eye. The highly lubricating hyaluronic acid increases comfort, but displaces films from the eye, reducing drug exposure and efficacy. Previous studies have shown that careful control of the surface interaction of the film with the eye is critical for improved re...

I LI Collagen and Hyaluronic Acid Interpenetrating Polymer Networks for Tissue